In a new study published in Cell Reports, researchers at the University of Freiburg reveal how a disordered protein segment helps connect two key steps of gene expression: the reading of genes and the ...
High-risk neuroblastoma kills roughly half of affected children because the tumor can switch cell identity and evade therapy. By combining single-cell multi-omics with spatial transcriptomics, ...
The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...
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