In summary, macrophages secrete IFN-β, activating the IFN-β-IFNAR-p-STAT1 axis in MICFs, leading to increased secretion of CCL2/7/12 chemokines and subsequent recruitment of more IFN-β-secreting ...
A paper, "Macrophages suppress cardiac reprogramming of fibroblasts in vivo via IFN-mediated intercellular self-stimulating circuit," published in Protein & Cell uncovers a previously unappreciated ...
The treatment, currently designated HTX-001, is an antisense oligonucleotide, or ASO, that targets Wisper and reduces the ...
After birth, the human heart loses its regenerative capacity almost completely. Damage to the heart muscle—for example, due to a heart attack—therefore usually leads to a permanent loss of function in ...
The research uncovers a previously unappreciated mechanism by which macrophages influence the fate of CFs post-MI. It demonstrates that macrophage-derived IFN-β stimulates the IFN-β-IFNAR-p-STAT1 axis ...
Please provide your email address to receive an email when new articles are posted on . Remote reprogramming for implantable cardiac devices was associated with an improvement in clinic workflow.
People with obesity and type 2 diabetes are at high risk of blood vessel damage. This risk depends not only on the genes a ...
(A) Representative M-mode echocardiography of short axis and representative PW-mode echocardiography of four-chamber section. (B) Left ventricular ejection fraction (EF%). (C) Left ventricular ...
Zhou’s study, "TBX20 improves contractility and mitochondrial function during direct human cardiac reprogramming," was recently published in Circulation. The most common cause of death worldwide is ...
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